From Ancient "Forget-Sorrow" Herb to Modern Science: Dayliflora™ and the Gut-Brain Axis

Views: 0     Author: Site Editor     Publish Time: 2026-05-28      Origin: Site

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[Image] Fresh Hemerocallis citrina flowers in bloom, golden yellow petals

1. Product Overview

Dayliflora™ Lemon Daylily Extract Powder is a proprietary branded ingredient developed by World-Way Biotechnology. It is derived from the open flowers of Hemerocallis citrina Baroni (commonly known as lemon daylily or "forget-sorrow herb" in traditional Chinese culture), using a patented water extraction process. This product targets the "mood and sleep balance" market segment and stands out among natural antidepressant ingredients for its unique gut-brain axis dopamine conversion mechanism. Dayliflora™ is protected by a Chinese invention patent application (No. 202610106975.5) and is supported by multiple SCI publications, making it a breakthrough innovation in the natural mood health space.

2. Botanical / Source Profile

• Botanical Name: Hemerocallis citrina Baroni

• Family: Asphodelaceae (formerly Liliaceae)

• Common Names: Lemon daylily, yellow flower vegetable, forget-sorrow herb

• Part Used: Open flowers (optimal at bud-to-early-bloom stage)

• Origin: China and East Asia

• Cultivation: Hunan, Jiangsu, Gansu provinces, China

In traditional Chinese medicine, daylily has been used for centuries as a natural mood enhancer. According to the Compendium of Materia Medica (《Bencao Gangmu》), daylily can "tranquilize the five organs, brighten the eyes, relieve vexation and heat, and bring happiness without worry." Folk remedies such as "daylily forget-sorrow soup" have been passed down through generations. World-Way selects premium lemon daylily varieties and employs a full-flower water extraction process to maximize the preservation of bioactive compounds.

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[Image] Dayliflora™ extract powder, fine texture on white background

3. Active Ingredients & Mechanism of Action

The core bioactive compounds in Dayliflora™ are a class of quinic acid derivatives, notably Compound 2 (3-O-p-coumaroylquinic acid) and Compound 4 (4-O-p-coumaroylquinic acid). These natural polyphenols are the key drivers of its antidepressant effects.

Gut-Brain Axis Dopamine Conversion Pathway:

  Step 1: Active compounds enter the gut and are hydrolyzed by gut microbial esterases and transaminases to produce Dopa;

  Step 2: Dopa crosses the blood-brain barrier (BBB) into the central nervous system;

  Step 3: Dopa is converted to dopamine by dopa decarboxylase, and further to norepinephrine by β-hydroxylase;

  Step 4: Elevated dopamine and norepinephrine levels directly improve mood states;

  Step 5: Upregulation of BDNF (brain-derived neurotrophic factor) helps repair neural damage, while increased SOD and decreased MDA reduce oxidative stress.

4. Health Benefits & Research Evidence

4.1 Antidepressant & Mood Regulation (Core Benefit)

In chronic unpredictable mild stress (CUMS) mouse models, Hemerocallis citrina extract demonstrated antidepressant effects comparable to fluoxetine (Prozac), a standard pharmaceutical antidepressant. Behavioral tests including sucrose preference, tail suspension, and forced swim tests all confirmed significant improvement in depression-like behaviors.

4.2 Stress & Anxiety Relief

Volunteer trials showed that Dayliflora™ significantly relieved symptoms such as irritability, chest tightness, unexplained crying, and self-doubt. Users also reported improved sleep quality (faster sleep onset, fewer dreams) and better digestive function (relief from constipation).

4.3 Neuroprotection & Antioxidant Activity

The extract significantly increases superoxide dismutase (SOD) activity in the cerebral cortex and hippocampus, reduces malondialdehyde (MDA) levels, and decreases the inflammatory cytokine IL-6. It also upregulates BDNF levels, providing neuroprotective benefits.

4.4 Digestive Health Support

By modulating the gut microbiome, the active compounds in lemon daylily not only participate in dopamine conversion but also improve the gut microenvironment, promoting the growth of beneficial bacteria and providing auxiliary relief for functional indigestion.

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[Image] Conceptual illustration of gut-brain dopamine conversion pathway

5. Applications & Market Positioning

Recommended Dosage: 1,000–2,000 mg per day.

Recommended Formats: Thanks to its water-extraction process and excellent cold-water solubility, it is ideal for instant drink powders, ready-to-drink beverages, tablets/compressed candies, hard capsules, and functional snacks.

Target Applications:

• Mood health functional foods (e.g., "happy water," "forget-sorrow tea")

• Stress management supplements for high-pressure professionals and students

• Sleep aid products targeting stress-induced temporary insomnia

• Women's health products, especially for menopausal mood disorders

• Functional snacks (stress-relief gummies, mood chocolates)

Market Positioning: Within World-Way's product matrix, Dayliflora™ anchors the "mood/sleep balance" segment, complementing Snoozana® (pumpkin seed/GABA pathway for deep sleep). Its key differentiation lies in matching clinical antidepressant efficacy without pharmaceutical side effects.

6. Target Audience

• Individuals with mild-to-moderate depression or anxiety seeking natural solutions

• High-pressure professionals dealing with work stress, burnout, and emotional fatigue

• Students experiencing academic pressure, exam anxiety, and self-doubt

• Menopausal women with mood disorders including irritability and depression

• People with stress-induced insomnia seeking better sleep naturally

• Consumers sensitive to chemical drug side effects looking for plant-based alternatives

7. Conclusion

Dayliflora™ Lemon Daylily Extract Powder represents World-Way Biotechnology's innovative fusion of traditional Chinese herbal wisdom and modern science. Its unique gut-brain dopamine conversion mechanism is groundbreaking in the natural mood health space. Backed by animal studies showing efficacy comparable to leading antidepressants, supported by multiple SCI publications and a pending patent, Dayliflora™ offers functional food and supplement brands a compelling natural mood health ingredient that perfectly aligns with today's consumer demand for "natural stress relief" and "authentic happiness from within."

We look forward to working with you to develop cost effective products and long term relationships with mutual benefit.

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