Views: 8 Author: Site Editor Publish Time: 2022-05-05 Origin: Site
Modified spike proteins from SARS-CoV-2 can be stopped by a common "weed" that is wiped out of the lawn every year. A study by a German university found that the common dandelion (Taraxacum officinale) can block the binding of spike proteins to ACE2 cell surface receptors in human lung and kidney cells. Water-based dandelion extracts taken from the dried leaves of this plant are effective against spike protein D614 and a range of mutant strains, including D614G, N501Y, K417N and E484K.
Dandelion extract blocks SARS CoV-2 spike protein and its variants
The researchers used high-molecular-weight compounds taken from water-based dandelion extracts and tested them in human HEK293-hACE2 kidneys and A549-hACE2-TMPRSS2 lung cells. Dandelions block protein interactions between the S1 subunit of spike protein and the human ACE2 cell surface receptor. The same is true for mutations in the spike protein of the main variants in circulation, including the British (B.1.1.7), South Africa (B.1.351), and Brazilian (P.1) variants.
Dandelion extract prevents SARS-CoV-2 spur-phenotype lentiviral particles from attaching to lung cells and blocks an inflammatory process called interleukin-6 secretion. Since the study was conducted in vitro, further clinical studies are needed to understand how dandelion extract is absorbed and utilized in the body's biological systems.
Since vaccines weaken herd immunity, natural herbs promise real prevention, more immunity
Despite tens of billions of public funds being poured into experimental vaccine development and advocacy campaigns, the world is battling new respiratory infections as SARS-CoV-2 mutates into different variants under pressure. There is no evidence that coronaviruses can be eradicated from the planet, so human adaptability will be key to the future. Dandelion extract is one of many herbs that will assist in a healthy immune response. Even better, dandelion extract can be shown to be completely protected against infection because it blocks the precise channels of nail protein attachment and causing the virus to replicate.
Other natural compounds have been investigated using molecular docking studies. Nobiletin is a flavonoid isolated from citrus peel. Neohesperidin, a derivative of hesperidin, is a flavonoid glycoside found in citrus fruits. Glycyrrhizic acid is a molecular compound extracted from the root of licorice. All three natural substances also prevent spike proteins from binding to ACE2 receptors. Water-alcohol pomegranate peel extract blocks spike protein on ACE2 receptors with a 74% efficacy. When its main ingredients were tested individually, punicalagin had a 64% efficacy and ellagic acid had a 36% efficacy.
These natural compounds (along with dandelion extracts) can be easily mass-produced, combined, and deployed as medicines to prevent all future mutations of spike proteins. These herbs are generally considered safe, and there are no known cases of dandelion leaf extract overdose. According to the European Scientific Society for Phytotherapy, the recommended dose of dandelion leaves is 4-10 grams soaked in hot water up to three times a day.
The study authors warn that relying on vaccines is risky and dangerous, not only for individual health, but also for herd immunity. Dependence on vaccines focused only on the enhancement of antibodies, which proved to be a high-risk intervention with a short effect. Vaccine injuries have been reported frequently. Reinfection after vaccination is also common because the vaccine puts pressure on the original modified spike protein to mutate.
The author concludes. "Therefore, factors such as low toxicity to humans and effective binding inhibition of five associated spike mutations to human ACE2 receptors reported here in vitro encourage t. A more in-depth analysis of the effectiveness of Taraxacum officinale in the prevention of SARS-CoV-2 is now needed to further confirm the clinical evidence. "